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. 2022 Dec 13;23(24):15798. doi: 10.3390/ijms232415798
2K1C two-kidney: one-clip (2K1C) Goldblatt hypertension
ACE angiotensin-converting enzyme
Agtr1a −/− mutant mice with whole-body deletion of the angiotensin II AT1a receptor
Ang I angiotensin I
Ang II angiotensin II
AT1 (AT1a) type 1 (1a) receptor for Ang II
GFR glomerular filtration rate
iL-Sglt2-Cre mutant mice with tissue-specific expression of Cre recombinase selectively in the proximal tubules of the kidney driven by the sodium and glucose cotransporter 2 (Sglt2) promoter
NHE3 the Na+/H+ exchanger 3
PT-Agtr1a−/− mutant mice with genetic deletion of AT1 (AT1a) receptors selectively in the proximal tubules of the kidney
PT-Nhe3−/− mutant mice with genetic deletion of the Na+/H+ exchanger 3 (NHE3) selectively in the proximal tubules of the kidney
RAS the renin-angiotensin system
WT wild-type mice