Rate difference of averted COVID-19 severe cases and deaths between vaccinated and unvaccinated individuals in Brazilian states in the population between 20 and 59 years, from January 31, 2021, to January 31, 2022. Data are the mean daily rate difference per 100,000 population. (a) Individuals at least partially vaccinated were those who received one or more doses of the COVID-19 vaccine. (b) Individuals who were fully vaccinated were those who completed the vaccine schedule. (c) Individuals who received the booster shot.