Figure 6.

Chronic intermittent hypoxia promotes BAT-specific insulin resistance. (A) Representative ¹⁸F-Fluorodeoxyglucose (FDG) absorption images demonstrating the anatomical location of BAT. (B) Quantification of the ¹⁸F-FDG consumption in total fat, demonstrating reduction in IH, compared with RA in total body fat (left panel) and BAT (right panel) (n = 3–5). (C,D) Western blot analysis of phosphorylated AKT(Ser473) protein levels normalized to total AKT in BAT following i.p. insulin stimulation (n = 3–4).