Table 4.
Risk factor analysis for first and second trimester pregnancy loss.
| Risk Factors * | First Trimester Pregnancy Loss (OR–95% CI) |
p-Value | Second Trimester Pregnancy Loss (OR–95% CI) |
p-Value |
|---|---|---|---|---|
| FVL heterozygous | 2.54 (1.33–4.96) | 0.036 | 1.82 (1.24–3.25) | 0.049 |
| FVL homozygous | 3.66 (1.85–6.11) | 0.001 | 2.27 (1.51–3.88) | 0.007 |
| PT heterozygous | 2.79 (1.27–3.82) | 0.022 | 2.81 (1.58–4.33) | 0.001 |
| FVL and PT compound | 3.11 (1.89–6.18) | 0.001 | 3.24 (1.80–5.76) | 0.001 |
| Protein C deficiency | 2.15 (1.32–3.93) | 0.009 | 2.98 (1.75–5.04) | 0.001 |
| Protein S deficiency | 2.25 (1.46–3.23) | 0.001 | 1.93 (1.16–2.83) | 0.012 |
| APS antibodies | 4.47 (2.03–6.32) | 0.001 | 3.85 (1.83–5.41) | 0.001 |
| MTHFR gene mutation | 2.02 (1.24–3.32) | 0.017 | 2.48 (1.37–4.29) | 0.001 |
| Glycoprotein Ia polymorphism | 1.97 (1.08–3.40) | 0.033 | 3.61 (1.22–4.94) | 0.001 |
* Data adjusted for age and body mass index; CI—Confidence Interval; OR—Odds Ratio.