Figure 2.
CM- and non-CM-specific modRNA expression platform. (A) Experimental design using two modRNA-based constructs to deliver any gene exclusively in CMs. (B) Schematic diagram showing CM-specific GFP modRNA expression in the mouse heart 1 day after MI and myocardial delivery of both modRNA constructs (Green wavy line represents modRNA which codes for gene of interest (GFP) would be delivered).