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Binding constants between cannabinoids and EGFR-TK determined from SPR kinetic analysis.
| Analyte | ka (102/(M∗s)) | kd (10−3/s) | KD (μM) |
|---|---|---|---|
| CBD | 3.92 (±2.06) | 3.28 (±5.24 × 10−3) | 8.35 (±6.10) |
| CBG | 2.64 (±0.69) | 1.48 (±4.80 × 10−3) | 5.61 (±1.61) |
| CBN | 0.94 (±0.24) | 3.02 (±1.31 × 10−3) | 32.1 (±8.85) |
Values are mean ± SD.
