Table 2.
Activity of selected AMPDs against MDR bacteria
| S. maltophiliaa | P. aeruginosa PA14 | P. aeruginosa ZEM-1A | E. cloacae | K. pneumoniae OXA-48 | P. aeruginosa ZEM9A | B. cenocepacia | S. aureus Newman | |
|---|---|---|---|---|---|---|---|---|
| sr-X18 | 4 | 8 | 8 | 16 | 16 | 64 | >64 | >64 |
| sr-X22 | 4 | 4 | 4 | >64 | 32 | >64 | >64 | >64 |
| L-X22 | 4 | 4 | 4 | 4 | 8 | 32 | >64 | >64 |
| D-X22 | 4 | 4 | 4 | 8 | 4 | 8 | >64 | 64 |
| sr-T25 | 8 | 4 | 4 | 8 | >64 | 16 | >64 | >64 |
| L-G3KL | 8 | 2–4 | 4 | 8 | >64 | 16 | >64 | >64 |
| L-T7 | 4 | 8 | 4 | 8 | 16 | 8 | >64 | >64 |
| PMB | 4 | 0.5 | 0.5 | 0.5 | 1 | 64 | >64 | >64 |
a
MIC in μg/mL was measured in MH medium at pH 7.4 after incubation for 16–20 h at 37°C. Each result represents two independent experiments performed in duplicate.