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. 2022 Mar 9;39(12):3123–3136. doi: 10.1007/s11095-022-03212-2

Table II.

Concentrations of stabilizers in the aqueous solution for CEL crystallizations and the resulting concentration when 40 % (w/w) MF was added to the solution

Polymer Type & Name Concentration / % (w/w) Resulting conc. with 40 % MF / % (w/w)
HPMC Substitution Type 2910 Pharmacoat® 603 2.44 1.46
Pharmacoat® 645 1.80 1.08
Pharmacoat® 606 1.48 0.89
Pharmacoat® 615 0.87 0.52
Metolose® 60SH-50 0.55 0.33
Methocel™ E4M 0.18 0.11
Substitution Type 2208 Methocel™ K4M 0.21 0.13
HPC SSL SFP 3.32 1.99
L 1.26 0.76
M 0.31 0.19
HEC Natrosol™ 250 G Pharm 0.32 0.19
PVP Kollidon® 90 F 1.25 0.75
PVPVA Kollidon® VA 64 7.50 4.50
PVA-PEG Kollicoat® IR 5.00 3.00
PS80 Tween 80 0.0080 0.0048