Table II.
Concentrations of stabilizers in the aqueous solution for CEL crystallizations and the resulting concentration when 40 % (w/w) MF was added to the solution
Polymer | Type & Name | Concentration / % (w/w) | Resulting conc. with 40 % MF / % (w/w) | |
---|---|---|---|---|
HPMC | Substitution Type 2910 | Pharmacoat® 603 | 2.44 | 1.46 |
Pharmacoat® 645 | 1.80 | 1.08 | ||
Pharmacoat® 606 | 1.48 | 0.89 | ||
Pharmacoat® 615 | 0.87 | 0.52 | ||
Metolose® 60SH-50 | 0.55 | 0.33 | ||
Methocel™ E4M | 0.18 | 0.11 | ||
Substitution Type 2208 | Methocel™ K4M | 0.21 | 0.13 | |
HPC | SSL SFP | 3.32 | 1.99 | |
L | 1.26 | 0.76 | ||
M | 0.31 | 0.19 | ||
HEC | Natrosol™ 250 G Pharm | 0.32 | 0.19 | |
PVP | Kollidon® 90 F | 1.25 | 0.75 | |
PVPVA | Kollidon® VA 64 | 7.50 | 4.50 | |
PVA-PEG | Kollicoat® IR | 5.00 | 3.00 | |
PS80 | Tween 80 | 0.0080 | 0.0048 |