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. 2022 Dec 20;24(12):799–808. doi: 10.1007/s11920-022-01388-3

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Downselection process for testing medications to be applied to individuals who are able to self-administer. Downselection process for medications currently available in US Army battalion aid stations or medic bags to test for performance effects and ASR symptom management efficacy. Downselection criteria were fast absorption rate, ease of administration, and mechanism of action. Of 127 medications available, 56 medications were found to be worthy of consideration for performance testing. Preferred criteria was a mechanism of action previously implicated in the stress response