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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2022 Nov 3;43(1):79–91. doi: 10.1161/ATVBAHA.121.317735

Figure 4: Platelet dependent thrombin generation is increased in aged pSOD2-KO mice.

Figure 4:

Platelet rich plasma was prepared from young and aged platelet-specific pSOD2-KO mice or control littermates, triggered with tissue factor and thrombin generation was analyzed using Calibrated Automated Thrombogram (CAT, Diagnostica Stago). A. Representative thrombin generation curves, B. thrombin peak and C. endogenous thrombin potential (ETP). Data are presented as mean ± SE and analyzed with two-way ANOVA with Tukey’s test for multiple comparisons. N = 6 per group.