Table 2.

Regression analysis for MET-score and ECAS/ICAS

Association of LTPA with ICAS
Characteristic	Model 1	Model 2	Model 3
	OR (95% CI)	OR (95% CI)	OR (95% CI)
≥50%	0.98 (0.96–0.99)	0.98 (0.97–1.00)	0.99 (0.97–1.00)
≥70%	0.96 (0.94–0.99)	0.97 (0.94–0.99)	0.97 (0.94–0.99)
Association of LTPA with ECAS
Characteristic	Model 1	Model 2	Model 3
	β-Estimate (95% CI)	β-Estimate (95% CI)	β-Estimate (95% CI)
Number of carotid plaques	0.001 (−0.004–0.005)	0.008 (−0.003–0.006)	0.002 (−0.003–0.006)
cIMT	0.0001 (−0.0001–0.0002)	0.0001 (−0.0001–0.0002)	0.0001 (−0.0001–0.0003)

LTPA = leisure time physical activity; MET-score = metabolic equivalent score; OR = odds ratio; CI = confidence interval; ICAS = intracranial artery stenosis; ECAS = extracranial carotid artery stenosis; cIMT = carotid intima-media thickness

Model 1: adjusted for age, sex, race and ethnicity, high school completion, and insurance status

Model 2: model 1 additionally adjusted for body mass index, hypertension, diabetes mellitus, hyperlipidemia, current smoking

Model 3: model 1 additionally adjusted for body mass index, systolic and diastolic blood pressure, years of hypertension, number of anti-hypertensive medications, blood glucose, years of diabetes mellitus, number of anti-glycemic medications, low-density lipoprotein, high-density lipoprotein, triglycerides, statin use, years smoked, and packs per day.