Table 2.
Copper therapeutics
| Compound | Potential therapeutic application | Chemical structure | Refs |
|---|---|---|---|
| Copper ionophores | |||
| Elesclomol | Menkes disease, Mitochondrial disorders, Cancer |
|
[80, 86] |
| CuATSM | ALS, Parkinson’s disease, Cancer |
|
[87, 88, 99] |
| CuGTSM | Alzheimer’s disease, Cancer |
|
[89, 99] |
| Disulfiram | Cancer, Alcohol abuse drug |
|
[79] |
| Copper chelators | |||
| D-penicillamine | Wilson disease |
|
[90, 92] |
| Trientine | Wilson disease |
|
[90, 92] |
| Tetrathiomolybdate | Wilson disease |
|
[90, 92, 93] |