Table 1.
Fifty-three proteins found more abundant in the surface fraction from SF-sEVs.
| Accession | Gene name | Description | # Repl. | PSM (Av) | nPSM (Av) |
|---|---|---|---|---|---|
| P04279 | SEMG1 | Semenogelin-1 | 3 | 628.3 | 8.10 |
| Q02383 | SEMG2 | Semenogelin-2 | 3 | 394.0 | 5.05 |
| P15144 | ANPEP | Aminopeptidase N | 3 | 133.7 | 1.74 |
| P02751 | FN1 | Fibronectin | 3 | 102.7 | 1.35 |
| P08473 | MME | Neprilysin (CD 10) | 3 | 83.3 | 1.09 |
| P49327 | FASN | Fatty acid synthase | 3 | 77.7 | 0.98 |
| P12277 | CKB | Creatine kinase B-type | 3 | 72.7 | 0.95 |
| P10909 | CLU | Clusterin | 3 | 71.7 | 0.93 |
| P04264 | KRT1 | Keratin, type II cytoskeletal 1 | 3 | 71.7 | 0.90 |
| P60709 | ACTB | Actin, cytoplasmic 1 | 3 | 65.7 | 0.86 |
| P49221 | TGM4 | Protein-glutamine gamma-glutamyltransferase 4 | 3 | 66.3 | 0.85 |
| P02768 | ALB | Serum albumin | 3 | 65.7 | 0.84 |
| P15309 | ACPP | Prostatic acid phosphatase | 3 | 64.0 | 0.83 |
| P27487 | DPP4 | Dipeptidyl peptidase 4 | 3 | 63.0 | 0.82 |
| P13645 | KRT10 | Keratin, type I cytoskeletal 10 | 3 | 59.7 | 0.75 |
| P12273 | PIP | Prolactin-inducible protein | 3 | 57.0 | 0.73 |
| P07900 | HSP90AA1 | Heat shock protein HSP 90-alpha | 3 | 55.3 | 0.71 |
| P08238 | HSP90AB1 | Heat shock protein HSP 90-beta | 3 | 52.3 | 0.67 |
| P02788 | LTF | Lactotransferrin | 3 | 50.7 | 0.64 |
| O43451 | MGAM | Maltase-glucoamylase, intestinal | 3 | 49.0 | 0.63 |
| P11142 | HSPA8 | Heat shock cognate 71 kDa protein | 3 | 45.3 | 0.58 |
| P0DMV9 | HSPA1B | Heat shock 70 kDa protein 1B | 3 | 43.7 | 0.56 |
| P35908 | KRT2 | Keratin, type II cytoskeletal 2 epidermal | 3 | 41.7 | 0.53 |
| P35579 | MYH9 | Myosin-9 | 3 | 41.0 | 0.53 |
| Q8WUM4 | PDCD6IP | Programmed cell death 6-interacting protein | 3 | 41.0 | 0.53 |
| P35527 | KRT9 | Keratin, type I cytoskeletal 9 | 3 | 41.3 | 0.52 |
| P80723 | BASP1 | Brain acid soluble protein 1 | 3 | 39.7 | 0.51 |
| P13796 | LCP1 | Plastin-2 | 3 | 39.3 | 0.51 |
| P07288 | KLK3 | Prostate-specific antigen | 3 | 36.3 | 0.47 |
| P0CG48 | UBC | Polyubiquitin-C | 3 | 35.0 | 0.46 |
| Q9Y3R5 | DOP1B | Protein dopey-2 | 3 | 35.0 | 0.44 |
| P62258 | YWHAE | 14-3-3 protein epsilon | 3 | 33.7 | 0.44 |
| P68371 | TUBB4B | Tubulin beta-4B chain | 3 | 33.7 | 0.43 |
| P14618 | PKM | Pyruvate kinase PKM | 3 | 32.3 | 0.41 |
| Q96KP4 | CNDP2 | Cytosolic non-specific dipeptidase | 3 | 31.7 | 0.41 |
| Q14204 | DYNC1H1 | Cytoplasmic dynein 1 heavy chain 1 | 3 | 32.7 | 0.41 |
| P04406 | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase | 3 | 31.7 | 0.40 |
| O14494 | PLPP1 | Phospholipid phosphatase 1 | 3 | 30.0 | 0.40 |
| P15311 | EZR | Ezrin | 3 | 30.7 | 0.39 |
| P68104 | EEF1A1 | Elongation factor 1-alpha 1 | 3 | 30.7 | 0.39 |
| O95716 | RAB3D | Ras-related protein Rab-3D | 3 | 29.0 | 0.38 |
| O00194 | RAB27B | Ras-related protein Rab-27B | 3 | 28.7 | 0.37 |
| P04792 | HSPB1 | Heat shock protein beta-1 | 3 | 27.7 | 0.36 |
| P00738 | HP | Haptoglobin | 3 | 28.0 | 0.36 |
| O43707 | ACTN4 | Alpha-actinin-4 | 3 | 27.3 | 0.35 |
| P04075 | ALDOA | Fructose-bisphosphate aldolase A | 3 | 27.3 | 0.35 |
| P07437 | TUBB | Tubulin beta chain | 3 | 27.7 | 0.35 |
| P00558 | PGK1 | Phosphoglycerate kinase 1 | 3 | 27.3 | 0.35 |
| P02538 | KRT6A | Keratin, type II cytoskeletal 6A | 1 | 30.0 | 0.13 |
| Q9BQE3 | TUBA1C | Tubulin alpha-1C chain | 1 | 28.0 | 0.12 |
| O95359 | TACC2 | Transforming acidic coiled-coil-containing protein 2 | 3 | 27.0 | 0.36 |
| P54652 | HSPA2 | Heat shock-related 70 kDa protein 2 | 3 | 27.3 | 0.35 |
| P55072 | VCP | Transitional endoplasmic reticulum ATPase | 3 | 26.7 | 0.35 |
#Repl.: Number of replicate MS samples in which the protein was identified; PSM (Av): Averaged number of PSMs in the replicates; nPSM (Av): normalized PSMs averaged.