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Semaglutide ameliorated HFD-induced obesity and blood glucose. (A) The body weight of NFD, HFD, HFD+sema group at the end of the 12th week of treatment was shown; (B) The liver weight of NCD, HFD, HFD+sema group at the end of the 12th week of treatment was shown; (C) Glucose tolerance was determined by IFGTT test; NCD, normal diet; HFD, high-fat diet; sema, semaglutide; IPGTT, Intraperitoneal glucose tolerance test. # means HFD vs Sema; * means NCD vs HFD.
