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. 2022 Dec 9;12:1074903. doi: 10.3389/fcimb.2022.1074903

Figure 1.

Figure 1

Galleria mellonella survival curves following infection with Cryptococcus neoformans. Untreated group, uninfected larvae; Saline group, larvae injected with saline; yeast group, larvae infected with C. neoformans without any treatment; POS, C. neoformans-infected larvae treated with posaconazole (POS) alone; POS+PP, C. neoformans-infected larvae treated with POS combined with pyrvinium pamoate (PP); ITR, C. neoformans-infected larvae treated with itraconazole alone; ITR+PP, C. neoformans-infected larvae treated with ITR combined with PP; VOR, C. neoformans-infected larvae treated with voriconazole alone; VOR+PP, C. neoformans-infected larvae treated with VOR combined with PP; FLU, C. neoformans-infected larvae treated with fluconazole alone; FLU+PP, C. neoformans-infected larvae treated with FLU combined with PP; AmB, C. neoformans-infected larvae treated with amphotericin B alone; AmB+PP, C. neoformans-infected larvae treated with AmB combined with PP; PP, C. neoformans-infected larvae treated with PP alone (*p< 0.05. ****p< 0.0001).