Table 3.
Development of models of actively induced EAN.
| Antigen | Animal studied | Reference |
|---|---|---|
| Tissue homogenates | ||
| Rabbit, bovine, dog, human, guinea pig sciatic nerve, rabbit ganglia | Rabbits | (119, 120) |
| Guinea pig sciatic nerve | White Leghorn chickens | (121) |
| Mouse, rabbit, dog, human nerve | White Swiss mice | (119) |
| Bovine, human, dog nerve | Guinea pigs | (119) |
| Peripheral myelin | ||
| Rabbit peripheral myelin | Rhesus monkeys | (122) |
| Rat, rabbit, bovine, human, guinea pig peripheral myelin | Lewis rats | (123) |
| Bovine peripheral myelin | Lewis rats | (124, 125) |
| Bovine peripheral myelin | Dark Agouti rats | (126) |
| Myelin proteins | ||
| P2 protein | Lewis rats | (127) |
| P0 protein | Lewis rats | (128) |
| Peripheral myelin protein 22 | Lewis rats | (129) |
| Peptides | ||
| Peptides of P2 protein | Lewis rats | (130, 131) |
| Peptides of P0 protein | Lewis rats | (132) |
| Peptides of P0 protein | C57/BL6 mice | (133, 134) |
| Protein/lipid complexes | ||
| P2 protein/phosphatidyl serine complex | Rhesus monkeys | (122) |
| P2 protein/phosphatidyl serine complex | Lewis rats | (127) |
| P2 protein/ganglioside complexes | Rabbit | (135) |
| Glycolipids | ||
| Galactocerebroside | Rabbit | (136) |
| GD1a | Rabbit | (137) |
| GM1 | Rabbit | (138) |
| GD1b | Rabbit | (136, 139–141) |