Table 8.

Sex differences in immune cell numbers and functions.

Immune cell	Difference between males and females
Percentage of lymphocytes in total leukocyte population	Higher in females (277)
CD4+:CD8+ ratio	Greater in females (278, 279)
Percentage of CD4+ T cells	Greater in females (280)
Percentage of CD8+ cells	Greater in males (280)
NK cell numbers	Higher in males (281)
Neutrophils	More activated in females (282)
Macrophage polarization	More M2 polarization in females (283)
Monocyte	Females show greater transcription of inflammatory genes (284)
Treg cell numbers	Increased in males (285)