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The main design of MR, identification of genetic instruments, and data and MR methods used for analyses. (A) Single-variable, multivariable, and reverse MR design for the association between eosinophil, basophil and lymphocyte with atopic dermatitis. (B) Genetic instrument selection of bidirectional MR for the associations between eosinophil, basophil and lymphocyte with atopic dermatitis. SNPs, single-nucleotide polymorphisms; MR, Mendelian randomization.
