TABLE 1.

Inclusion/exclusion criteria.

Inclusion criteria	Exclusion criteria
Male or female > 16 years old	Known sensitivity to any compound of the investigated products
Signed informed consent form	Pregnant or breastfeeding
No participation in similar study currently or during previous 6 months	Facial disease or having any facial cosmetic procedures within 3 months
Ability to follow the instructions from investigators and return to study center at established time	History of cosmetic product use within a fortnight that, in investigator’s opinion, could interfere with assessment
Last treatment was at least 2 months ago	Significant psychological and psychiatric disorders that could impair subjects’ ability to meet study requirements
Non responsive to previous treatments, either systemic, topical, or phototherapy	History of concurrent malignancy
Not receiving any drugs/cosmetic treatments that might interfere with current study	Any medical condition that, in investigator’s opinions, could prevent the subjects from participating in study