Table 1.
Baseline characteristics of patients.
| Characteristics | All patients N = 85, N (%) | ICI+Lenva N = 58, N (%) | ICI+Others N = 27, N (%) | P - value |
|---|---|---|---|---|
| Medical center | 0.183 | |||
| PUMCH | 63 (74.1) | 40 (69.0) | 23 (85.2) | |
| PLAGH | 22 (25.9) | 18 (31.0) | 4 (14.8) | |
| Age | 1 | |||
| < 65 | 67 (78.8) | 46 (79.3) | 21 (77.8) | |
| ≥ 65 | 18 (21.2) | 12 (20.7) | 6 (22.2) | |
| Sex | 0.508 | |||
| Female | 12 (14.1) | 7 (12.1) | 5 (18.5) | |
| Male | 73 (85.9) | 51 (87.9) | 22 (81.5) | |
| Viral Hepatitis | 0.804 | |||
| HBV | 66 (77.7) | 46 (79.3) | 20 (74.1) | |
| HCV | 3 (3.5) | 2 (3.5) | 1 (3.7) | |
| NBNC | 16 (18.8) | 10 (17.2) | 6 (22.2) | |
| Alcohol consumption | 0.791 | |||
| No | 63 (74.1) | 42 (72.4) | 21 (77.8) | |
| Yes | 22 (25.9) | 16 (27.6) | 6 (22.2) | |
| ECOG | 0.35 | |||
| 0 | 32 (37.7) | 23 (39.7) | 9 (33.3) | |
| 1 | 46 (54.1) | 32 (55.2) | 14 (51.9) | |
| 2 | 7 (8.2) | 3 (5.2) | 4 (14.8) | |
| Child–Pugh | 1 | |||
| A | 61 (71.8) | 42 (72.4) | 19 (70.4) | |
| B | 24 (28.2) | 16 (27.6) | 8 (29.6) | |
| AFP (ng/ml) | 1 | |||
| < 400 | 53 (62.3) | 36 (62.1) | 17 (63.0) | |
| ≥ 400 | 32 (37.7) | 22 (37.9) | 10 (37.0) | |
| Tumor number | 0.660 | |||
| 1 | 6 (7.1) | 5 (8.6) | 1 (3.7) | |
| ≥ 2 | 79 (92.9) | 53 (91.4) | 26 (96.3) | |
| Tumor size | 0.625 | |||
| < 5 cm | 28 (32.9) | 18 (31.0) | 10 (37.0) | |
| ≥ 5 cm | 57 (67.1) | 40 (69.0) | 17 (63.0) | |
| Macrovascular invasion | 0.168 | |||
| No | 47 (55.3) | 29 (50.0) | 18 (66.7) | |
| Yes | 38 (44.7) | 29 (50.0) | 9 (33.3) | |
| Extrahepatic metastasis | 0.81 | |||
| No | 31 (36.5) | 22 (37.9) | 9 (33.3) | |
| Yes | 54 (63.5) | 36 (62.1) | 18 (66.7) | |
| BCLC staging | 1 | |||
| B | 9 (10.6) | 6 (10.3) | 3 (11.1) | |
| C | 76 (89.4) | 52 (89.7) | 24 (88.9) | |
| Previous systemic treatment | 0.477 | |||
| No | 55 (64.7) | 39 (67.2) | 16 (59.3) | |
| Yes | 30 (35.3) | 19 (32.8) | 11 (40.7) | |
| Previous locoregional treatment | 1 | |||
| No | 12 (14.1) | 8 (13.8) | 4 (14.8) | |
| Yes | 73 (85.9) | 50 (86.2) | 23 (85.2) |
PUMCH, Peking Union Medical College Hospital; PLAGH, Chinese Peoples’ Liberation Army General Hospital; HBV, hepatitis B virus; HCV, hepatitis C virus; NBNC, no HBV or HCV infection; AFP, alpha-fetoprotein; BCLC, Barcelona Clinic Liver Cancer.