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. 2022 Dec 9;12:1094657. doi: 10.3389/fonc.2022.1094657

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Copyright © 2022 Ding, Wei, Jiang, Wei, Deng and Yuan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction of a fatty acid metabolism-related signature in ccRCC patients. (A) The frequency of the top 10 genes with amplified or deleted CNVs of FMGs in the TCGA-KIRC cohort. (B) Heatmap analysis of 34 DEGs among FMGs. (C) Volcano plot depicting the distribution of DEGs. (D) 160 prognostic FMGs in the TCGA-KIRC dataset. (E) 67 prognostic FMGs in the MTAB dataset. (F) Venn plot identifying 52 overlapping prognostic FMGs. (G) LASSO Cox regression analysis of the 52 prognostic FMGs. (H) Plot depicting partial likelihood deviance of the LASSO regression. (I) Corresponding coefficients of the 10 FMGs.