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. 2022 Dec 9;3:1012598. doi: 10.3389/fragi.2022.1012598

TABLE 2.

Fully adjusted linear regression models of MedDiet scores (MEDAS, MEDAS Continuous and Pyramid) with cognitive outcomes, MedDiet score, sex, age, education and APOE shown. Fully Adjusted Model: MedDiet Score, sex, age, education, family history, APOE, physical activity, smoking, sleep, body mass index, hypertension, hypercholesterolemia, hyperglycaemia, diabetes, stroke, antihypertensive medication use, diabetic medication use. AI, attention index; DMI, delayed memory index; FMT, Four Mountains Test; IMI, immediate memory index; LI, language index; m, male; RBANS, Repeatable Battery for the Assessment of Neuropsychological Status; VCI, visuoconstructional index.

FMT RBANS total AI DMI IMI LI VCI
MEDAS
β SE p β SE p β SE p β SE p β SE p β SE p β SE p
Dietary score 0.12 0.04 0.004 −0.18 0.20 0.37 −0.23 0.23 0.32 −0.05 0.23 0.82 0.13 0.21 0.54 −0.19 0.16 0.22 −0.24 0.22 0.29
Age −0.13 0.01 <0.001 −0.24 0.05 <0.001 −0.23 0.06 <0.001 −0.26 0.05 <0.001 −0.29 0.05 <0.001 −0.05 0.04 0.15 −0.07 0.05 0.18
Sex (m) 0.71 0.15 <0.001 −2.58 0.69 <0.001 −0.02 0.81 0.98 −3.00 0.79 <0.001 −.38 0.72 <0.001 −5.41 0.55 <0.001 3.80 0.77 <0.001
Education 0.08 0.02 <0.001 1.28 0.09 <0.001 1.19 0.11 <0.001 0.89 0.10 <0.001 0.97 0.09 <0.001 0.50 0.07 <0.001 1.03 0.10 <0.001
APOE (no) 0.19 0.14 0.18 1.45 0.69 0.03 0.09 0.80 0.91 2.86 0.78 <0.001 3.38 0.71 <0.001 −0.04 0.54 0.95 −0.74 0.76 0.33
MEDAS continuous
Dietary score 0.07 0.05 0.12 −0.25 0.22 0.27 −0.37 0.26 0.15 −0.08 0.25 0.75 0.19 0.23 0.41 −0.13 0.17 0.45 −0.46 0.25 0.06
Age −0.13 0.01 <0.001 −0.24 0.05 <0.001 −0.23 0.06 <0.001 −0.26 0.05 <0.001 −0.29 0.05 <0.001 −0.05 0.04 0.17 −0.07 0.05 0.19
Sex (m) 0.69 0.15 <0.001 −2.57 0.69 <0.001 −0.01 0.81 0.99 −3.00 0.78 <0.001 −4.38 0.72 <0.001 −5.39 0.54 <0.001 3.80 0.77 <0.001
Education 0.08 0.02 <0.001 1.27 0.09 <0.001 1.18 011 <0.001 0.89 0.10 <0.001 0.97 0.09 <0.001 0.49 0.07 <0.001 1.02 0.10 <0.001
APOE (no) 0.19 0.14 0.19 1.48 0.69 0.03 0.15 0.80 0.86 2.88 0.78 <0.001 3.36 0.71 <0.001 −0.04 0.54 0.95 −0.66 0.76 0.39
Pyramid
Dietary score 0.009 0.05 0.85 −0.18 0.23 0.45 −0.58 0.27 0.04 0.20 0.27 0.46 0.33 0.24 0.18 −0.14 0.18 0.45 −0.47 0.26 0.07
Age −0.14 0.01 <0.001 −0.24 0.69 <0.001 −0.22 0.06 <0.001 −0.26 0.05 <0.001 −0.29 0.05 <0.001 −0.05 0.04 0.18 −0.07 0.05 0.22
Sex (m) 0.68 0.15 <0.001 −2.54 0.05 <0.001 0.04 0.81 0.96 −3.00 0.78 <0.001 −4.41 0.72 <0.001 −5.38 0.54 <0.001 3.85 0.77 <0.001
Education 0.08 0.02 <0.001 1.27 0.09 <0.001 1.18 0.11 <0.001 0.89 0.10 <0.001 0.97 0.09 <0.001 0.49 0.07 <0.001 1.02 0.10 <0.001
APOE (no) 0.20 0.14 0.16 1.45 0.69 0.03 0.14 0.80 0.86 2.83 0.78 <0.001 3.35 0.71 <0.001 −0.05 0.54 0.93 −0.71 0.76 0.36