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OP-D inhibited c-Myc expression in HCT116p53+/+ cells. HCT116p53+/+ cells were treated with OP-D (0, 20, or 40 μM) for 24 h. Cell lysates were performed for c-Myc, Pro-PARP, p-AKT, cyclin D1, CDK4, and β-actin by Western blotting. Data represent means ± SD. * p < 0.05 versus untreated control.
