Table 1.
Comparisons of clinical and laboratory characteristics in three subgroups.
| Variable | VAP (n = 17) | CAP with MV (n = 60) | CAP without MV (n = 39) | p-value |
|---|---|---|---|---|
| Clinical features at admission | ||||
| Length of hospitalization stay (days), median (IQR) | 27 (26) | 27.25 (25) | 13.5 (11.5) | 0.004 |
| Age at admission (years old), mean ± SD | 53.53 ± 18.02 | 54.65 ± 13.64 | 49.95 ± 15.65 | 0.31 |
| Disease duration of MG (years), median (IQR) | 1 (5.33) | 2 (4.93) | 2 (5) | 0.7 |
| Thymectomy, n (%) | 9 (52.94) | 30 (50) | 16 (41.03) | 0.67 |
| LOMG, n (%) | 9 (52.94) | 32 (53.3) | 17 (43.59) | 0.62 |
| IS within 1 year before hospitalization, n (%) | 3 (17.65) | 13 (21.67) | 16 (41.03) | 0.08 |
| CS within 1 year before hospitalization, n (%) | 11 (64.71) | 45 (75) | 31 (79.49) | 0.51 |
| MGFA classification, n (%) | ||||
| IIa | 2 (11.76) | 7 (11.67) | 7 (17.95) | 0.76 |
| IIb | 1 (5.88) | 5 (8.33) | 7 (17.95) | 0.34 |
| IIIa | 0 | 2 (3.33) | 2 (5.13) | 0.81 |
| IIIb | 0 | 12 (20) | 11 (28.21) | 0.04 |
| IVa | 0 | 0 | 1 | 0.53 |
| IVb | 2 (11.76) | 34 (56.67) | 11 (28.21) | <0.001 |
| V | 12 (70.59) | 0 | 0 | <0.001 |
| Baseline pneumonia score and laboratory test within 24 h | ||||
| CURB-65, median (IQR) | 0.5 (1) | 0 (1) | 0 (1) | 0.66 |
| SIPF, median (IQR) | 1 (1) | 1 (1) | 1 (1) | 0.14 |
| WBC count (×109/L), median (IQR) | 10.61 (4.45) | 9.8 (5.74) | 8.13 (6.75) | 0.22 |
| Lymphocyte (%), median (IQR) | 12.2 (11.3) | 7.1 (7) | 11.7 (17.85) | <0.001 |
| Absolute count of lymphocyte (/μl), median (IQR) | 1 (1.01) | 0.66 (0.73) | 1.19 (1.05) | 0.26 |
| Neutrophil (%), median (IQR) | 79.5 (16.8) | 86.05 (12.95) | 79.2 (19.05) | 0.047 |
| Absolute count of neutrophil (/μl), median (IQR) | 6.79 (4.92) | 8.57 (5.12) | 6.39 (8.15) | 0.48 |
| HCT (%), median (IQR) | 34.6 (8.4) | 36.7 (5.48) | 37.8 (10.7) | 0.28 |
| SO2 (%), median (IQR) | 98.9 (1.8) | 96.9 (3.7) | 97.75 (3.33) | 0.02 |
| PaCO2 (kPa), median (IQR) | 6 (1.14) | 5.665 (1.44) | 5.75 (1.04) | 0.9 |
| PaO2 (kPa), median (IQR) | 16.44 (8.73) | 13.92 (7.7) | 11.9 (5.77) | 0.51 |
| BE (mmol/L), median (IQR) | 2.3 (4.1) | 2.5 (5.68) | 2.3 (3.55) | 0.38 |
| Albumin (g/L), mean ± SD | 33.88 ± 5.85 | 33.68 ± 5.43 | 37 ± 4.63 | 0.008 |
| Globulin (g/L), mean ± SD | 37.24 ± 12.22 | 37.99 ± 10.66 | 32.52 ± 10.76 | 0.05 |
| A/G ratio, median (IQR) | 0.79 (0.42) | 0.86 (0.4) | 1.2 (0.53) | 0.03 |
IQR, interquartile range; LOMG, late-onset myasthenia gravis; HCT, hematocrit; WBC, white blood cell; SO2, oxygen saturation; PaO2, partial pressure of oxygen; PaCO2, carbon dioxide; BE, base excess; NLR, neutrophil-to-lymphocyte ratio.
P values less than 0.05 were highlighted in bold type.