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. 2022 Dec 9;12:1016728. doi: 10.3389/fcimb.2022.1016728

Table 2.

Univariate and multivariate logistic regression models for the severe course in the hospitalized MG patients with pneumonia.

Variables Univariate analysis * Multivariate analysis †
OR 95% CI p-value OR 95% CI p-value
Thymectomy Yes 1.43 0.64–3.28 0.38
No
IS within 1 year before admission Yes 0.39 0.16–0.96 0.04 0.59 0.2–1.71 0.33
No
CS within 1 year before admission Yes 0.85 0.31–2.23 0.74
No
Duration of MG 0.85 0.31–2.23 0.74
WBC count 1.07 0.99–1.18 0.11 1.01 0.91–1.12 0.92
Lymphocyte (%) 0.91 0.86–0.95 <0.001 0.88 0.75–0.96 0.02
Absolute number of lymphocytes 0.85 0.55–1.14 0.34
Neutrophil (%) 1.03 1.00–1.07 0.04 0.98 0.87–1.03 0.63
Absolute number of neutrophils 0.99 0.95–1.03 0.64
HCT 0.98 0.94–1.01 0.34
SO2 1.03 0.91–1.17 0.58
PaCO2 0.93 0.7–1.24 0.62
PaO2 0.1 0.96–1.04 0.82
BE 1.04 0.97–1.14 0.38
Albumin 0.88 0.8–0.96 0.003 0.87 0.75–0.13 0.05
Globulin 1.05 1.01–1.09 0.02 1.16 1.02–1.35 0.03
A/G ratio 0.27 0.1–0.66 0.006 14.15 0.56–444.21 0.11

OR, odds ratio; CI, confidence interval; CS, corticosteroid; IS, immunosuppressant; HCT, hematocrit; WBC, white blood cell; SO2, oxygen saturation; PaO2, partial pressure of oxygen; PaCO2, carbon dioxide; BE, base excess; NLR, neutrophil-to-lymphocyte ratio.

P values less than 0.2 in univariate analysis and less than 0.05 in multivariate analysis were highlighted in bold type.