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. 2022 Dec 9;13:1074289. doi: 10.3389/fmicb.2022.1074289

TABLE 4.

Comparison of mainstream nucleic acid detection platforms.

Platforms Company Principle Volume (cm) Weight (kg) Throughput Target Time (min)
FilmArray Biofire Nested PCR 39.3 × 25.4 × 16.5 7.3 1 24 60
GeneXpert Omni Cepheid Nested qPCR 8 × 11 × 23 1 1 1–2 30–60
Io system Atlas Genetics PCR 27.7 × 27.5 × 38.4 10 1 24 30
Cobas Liat IQuum qPCR 19 × 11.4 × 24.1 3.76 1 1–2 20
ID Now Abbott Molecular NEAR 21 × 15 × 19 3 1 1–2 5–13
RTisochip-W system CapitalBio NASBA 58.6 × 69.0 × (17.5 × 4) 33 × 4 16 19 90
iPonatic Sansure Biotech qPCR <10 1 1–2 15–45
Easy NET USTAR Biotech CPA 26 × 37 × 52 13 2 1–2 80–90

NEAR, nicking enzyme amplification reaction; CPA, crossing priming amplification.