TABLE 2.
List of overlapping regions and candidate genes identified using the iHS and XPCLR selection scan methods including, gene functions in reported species.
| BAT | Region start | Region end | XPCLR score | iHS value | Gene name | Gene function/phenotype | Species | References |
|---|---|---|---|---|---|---|---|---|
| 2 | 42.25 | 42.45 | 10.99 | 6.28 | GALNT13 | |||
| 3 | 17.55 | 17.6 | 11.54 | 6.15 | ENSBTAG0 | Novel gene/uncharacterized protein | — | — |
| 0000050002 | ||||||||
| 3 | 57.5 | 57.6 | 16.01 | 6.75 | CLCA4 | Rennin secretion, ion channel activity | Palubiski et al. (2020); Weir and Olschewski, (2006) | |
| CLCA1 | “ | “ | ||||||
| 3 | 57.55 | 57.65 | 12.65 | 6.75 | CLCA2 | “ | “ | |
| 5 | 83.45 | 83.55 | 16.65 | 8.19 | ITPR2 | Response to hypoxia | Human | Huerta-Sánchez et al. (2013); Jurkovicova et al. (2008); Manalo et al. (2005); Qu et al. (2015) |
| 8 | 48.4 | 48.5 | 43.83 | 6.23 | GDA | |||
| 12 | 29.6 | 29.7 | 11.17 | 6.31 | B3GLCT | Carbohydrate metabolic process, protein glycosylation, horn development, environment adaptation | Cattle, sheep | Ahbara et al. (2019); Flori et al. (2019); Pan et al. (2018) |
| 14 | 81.45 | 81.55 | 13.63 | 6.04 | COL14A1 | Protein binding, angiogenesis | Mice, rats, sheep, human | Chai et al. (2004); Copple et al. (2011); Wiener et al. (2021); Zhang et al. (2018) |
| 16 | 60.65 | 60.75 | 12.94 | 7.05 | SOAT1 | Cholesterol metabolic process | Insects, mice | Guan et al. (2020); Miron and Tirosh, (2019); Zuniga-Hertz and Patel, (2019) |
| AXDND1 | Response to bone fracture/bone synthesis | human | Pettersson-Kymmer et al. (2013) | |||||
| 28 | 14.5 | 15.5 | 18.81 | 6.94 | NUP133 | Regulate mitochondrial function and oxidative stress response | Mouse | Sunny et al. (2020) |
| ABCB10 | ATPase-coupled transmembrane transporter activity; regulates heme synthesis; Iron metabolism; reactive oxygen species | Mouse, zebrafish, human cell culture | Bayeva et al. (2013); Liesa et al. (2012); Seguin and Ward, (2018); Valverde et al. (2015); Yamamoto et al. (2014) | |||||
| ENSBTAG0 | Basal transcription, coactivators, and promotor recognition. | |||||||
| 0000034225 |