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. 2022 Dec 9;13:1055497. doi: 10.3389/fimmu.2022.1055497

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Copyright © 2022 Chu, Talano, Baxter-Lowe, Verbsky, Morris, Mahanti, Ayello, Keever-Taylor, Johnson, Weinberg, Shi, Moore, Fabricatore, Grossman, van de Ven, Shenoy and Cairo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neutrophil and platelet engraftment, cumulative incidence of Grade II-IV aGVHD and cGVHD, and whole blood and RBC donor chimerism. (A, B) The probability of neutrophil and platelet engraftment, (C) cumulative incidence of aGVHD, (D) cGVHD, (E) donor chimerism in whole blood, and (F) RBC (erythrocyte enriched fraction) were determined using the product limit method of Kaplan and Meier. Donor chimerism (% donor) was determined at 30d, 60d, 3-month, 6-month, 1 yr, and 2 yr post-HSCT. Panel E is peripheral blood and panel F represents RBC. Results are shown as the mean ± SEM. aGVHD, acute graft versus host disease; RBC, red blood cells; cGVHD, chronic graft versus host disease; HSCT, hematopoietic stem cell transplantation; SEM, standard error of the mean.