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. 2022 Dec 9;13:1055497. doi: 10.3389/fimmu.2022.1055497

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Copyright © 2022 Chu, Talano, Baxter-Lowe, Verbsky, Morris, Mahanti, Ayello, Keever-Taylor, Johnson, Weinberg, Shi, Moore, Fabricatore, Grossman, van de Ven, Shenoy and Cairo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Reconstitution of T, B, NK, and Treg cells. Absolute cell counts were determined for (A) CD4⁺ T-cells, (B) CD8⁺ T-cells, (C) B cells, (D) NK cells (CD3^-/CD56⁺), and (E) Treg (CD4⁺CD127^dimCD25^hi Foxp3⁺). Measurements were made at baseline (day -59) and 100, 180, 270, and 365 days after HSCT. Statistically significant differences between baseline and post-HSCT timepoints are indicated as **** P<0.0001, *** P<0.005, ** P<0.001, * P<0.05. Differences that are not significant are labeled, ns. NK, natural killer; Treg, regulatory T cells; HSCT, hematopoietic stem cell transplantation; ns, not significant.