FIG. 3.

Tissue depletion of CD4⁺ and CD8⁺ T cells following secondary infectious challenge of antibody-treated wild-type B6 mice. Seven days following a secondary C. trachomatis infection, mice were sacrificed and their genital tracts were removed and processed for immunohistochemical analysis. In vivo treatment: PBS (A to C), anti-CD4 (D to F), and anti-CD8 (G to I). In vitro immunohistochemical staining: anti-CD4 (A, D, and G), anti-CD8 (B, E, and H), and control rat Ig (C, F, and I). Representative tissues from two or three mice are shown. Tissues harvested at 3 days post secondary infectious challenge showed a similar staining pattern. Original magnification, ×300.