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. Author manuscript; available in PMC: 2023 Sep 7.
Published in final edited form as: J Am Soc Mass Spectrom. 2022 Aug 25;33(9):1784–1793. doi: 10.1021/jasms.2c00166

Table 4:

Number of total changes in classification when comparing the classification obtained for targets using only the low-fragmentation mass spectrum and when using all the is-CID mass spectra. Values above the diagonal indicate an improvement in the classification while values below the diagonal (bolded and italicized) indicate a drop in classification. In each cell, the left column indicates the number of changes when using FPIE as the scoring metric (along with a 0.7 a.u. scoring threshold) and the right column indicates the number of changes when using RevMF as the scoring metric.

Low-fragmentation only classification
Ideal Desirable Acceptable Non-Descriptive 1 Non-Descriptive 2 Undesirable
All is-CID spectra classification Ideal 10 9 0 3 58 66 0 1 0 1
Desirable 2 0 3 0 6 13 01 0 0 0
Acceptable 0 0 4 5 0 0 0 0 0 0
Non-Descriptive 1 12 0 0 0 0 0 0 2 1 0
Non-Descriptive 2 29 45 1 0 0 1 4 11 4 5
Undesirable 0 0 0 0 0 0 4 4 0 0