Figure 3.

Chromosome–based circos plots. Mean logFC values for CpG methylation load (CP over control) were calculated for sequential 1 Mbp intervals. There was a strong correlation between differential methylation in MBs and MTs (a). Scatterplots of values for each chromosome are shown for MBs (b) and MTs (c); values outside the 95% confidence interval of the average logFCs across the whole genome are red indicating significant hypermethylation in CP or blue for significant hypomethylation in CP. The gray ring shows points within the 95% CI for the overall data.