Table 2.
CpG sites that were differentially methylated in both MBs and MTs *.
| Position | MB LogFC | MB FDR Corrected p-Value | MT LogFC | MT FDR Corrected p-Value | Gene |
|---|---|---|---|---|---|
| chr2.0003882321 | 0.88 | 2.29 × 10−2 | 0.90 | 2.40 × 10−2 | |
| chr2.0029850455 | 1.24 | 6.74 × 10−4 | 1.32 | 1.11 × 10−5 | ALK |
| chr2.0033057636 | −0.84 | 3.40 × 10−3 | −0.85 | 1.94 × 10−2 | LINC00486 |
| chr2.0035092870 | −1.09 | 1.00 × 10−2 | −1.19 | 8.26 × 10−5 | AC012593.1 |
| chr2.0056193463 | 1.32 | 1.79 × 10−3 | 1.55 | 1.22 × 10−6 | RP11—481J13.1, AC011306.2 |
| chr2.0223166989 | 0.87 | 4.07 × 10−2 | 0.90 | 4.80 × 10−2 | CCDC140 |
| chr2.0235215325 | −1.05 | 6.08 × 10−4 | −1.08 | 6.49 × 10−4 | |
| chr3.0053784559 | 0.91 | 1.58 × 10−2 | 1.14 | 8.96 × 10−4 | CACNA1D |
| chr3.0060919598 | −0.85 | 1.89 × 10−3 | −0.86 | 3.09 × 10−2 | FHIT |
| chr3.0119863345 | 1.28 | 2.04 × 10−3 | 1.48 | 1.19 × 10−5 | GPR156 |
| chr3.0119990864 | −1.14 | 2.05 × 10−3 | −1.01 | 4.01 × 10−2 | GPR156 |
| chr3.0127606140 | −1.40 | 1.26 × 10−4 | −1.12 | 6.36 × 10−3 | |
| chr3.0182124231 | −1.14 | 3.82 × 10−2 | −1.15 | 5.10 × 10−3 | |
| chr3.0189791239 | −1.34 | 1.56 × 10−2 | −1.13 | 5.00 × 10−2 | LEPREL1 |
| chr3.0196595774 | −1.37 | 3.54 × 10−2 | −1.33 | 1.44 × 10−2 | SENP5 |
| chr4.0101719592 | −1.04 | 4.74 × 10−5 | −1.15 | 1.77 × 10−7 | EMCN |
| chr5.0011534641 | 0.90 | 2.48 × 10−2 | 1.05 | 7.82 × 10−3 | CTNND2 |
| chr5.0039219698 | 1.22 | 3.91 × 10−2 | 1.37 | 2.24 × 10−2 | FYB |
| chr5.0164483805 | −0.92 | 2.51 × 10−2 | −1.11 | 1.05 × 10−3 | CTC—340A15.2 |
| chr5.0166472226 | −1.03 | 1.03 × 10−2 | −1.16 | 4.86 × 10−4 | |
| chr6.0008948266 | 1.16 | 2.27 × 10−2 | 1.24 | 2.52 × 10−3 | |
| chr6.0016145414 | −1.17 | 2.94 × 10−4 | −1.24 | 9.54 × 10−5 | MYLIP |
| chr6.0019413218 | 0.81 | 2.95 × 10−3 | 0.86 | 1.70 × 10−2 | |
| chr6.0031008851 | 0.96 | 2.29 × 10−2 | 1.01 | 1.56 × 10−2 | RASSF3 |
| chr6.0154640863 | 1.37 | 9.68 × 10−3 | 1.34 | 3.64 × 10−3 | IPCEF1 |
| chr6.0161063597 | −2.29 | 3.71 × 10−3 | −1.62 | 2.31 × 10−2 | LPA |
| chr7.0016768868 | −0.75 | 1.18 × 10−2 | −1.03 | 1.03 × 10−5 | |
| chr7.0044621160 | 0.91 | 1.71 × 10−2 | 0.97 | 4.26 × 10−2 | TMED4 |
| chr7.0147581299 | −0.68 | 3.30 × 10−2 | −0.83 | 3.24 × 10−2 | CNTNAP2 |
| chr11.0123045794 | −1.36 | 1.13 × 10−3 | −1.54 | 2.08 × 10−6 | CLMP |
| chr11.0129565594 | 1.28 | 1.59 × 10−2 | 1.68 | 1.23 × 10−4 | |
| chr12.0003241735 | 1.19 | 4.26 × 10−3 | 1.04 | 3.25 × 10−2 | TSPAN9 |
| chr12.0026672531 | 1.00 | 4.67 × 10−2 | 1.28 | 1.68 × 10−2 | ITPR2 |
| chr12.0048360477 | −1.69 | 3.13 × 10−4 | −1.10 | 4.25 × 10−2 | TMEM106C |
| chr12.0054366343 | 0.87 | 4.94 × 10−2 | 1.07 | 3.53 × 10−2 | HOTAIR |
| chr12.0055783991 | 1.19 | 4.36 × 10−2 | 1.29 | 2.11 × 10−2 | |
| chr12.0083436417 | 1.62 | 4.94 × 10−3 | 2.14 | 6.72 × 10−5 | TMTC2 |
| chr12.0114887843 | 1.42 | 1.84 × 10−4 | 0.62 | 4.91 × 10−2 | |
| chr12.0116068191 | −1.32 | 1.42 × 10−2 | −1.58 | 5.07 × 10−6 | RP11—1028N23.4 |
| chr12.0128167651 | 1.13 | 3.28 × 10−2 | 1.57 | 8.87 × 1014 | |
| chr12.0131689822 | 1.29 | 2.19 × 10−2 | 1.74 | 5.09 × 10−5 | RP11—638F5.1 |
| chr13.0021286449 | −1.10 | 4.87 × 10−2 | −1.33 | 2.22 × 10−2 | IL17D |
| chr13.0027424109 | 1.51 | 1.23 × 10−2 | 1.56 | 5.47 × 10−4 | |
| chr13.0033220266 | −1.24 | 5.87 × 10−3 | −1.31 | 2.18 × 10−3 | PDS5B |
| chr13.0047191668 | −1.30 | 6.51 × 10−3 | −1.34 | 6.36 × 10−3 | LRCH1 |
| chr13.0093896533 | 1.50 | 2.96 × 10−2 | 2.41 | 2.86 × 10−5 | GPC6 |
| chr13.0099687193 | 1.01 | 3.54 × 10−2 | 1.06 | 4.85 × 10−2 | DOCK9 |
| chr13.0107176083 | −1.69 | 7.74 × 10−3 | −1.68 | 1.29 × 10−2 | EFNB2 |
| chr13.0109856377 | −1.48 | 4.00 × 10−2 | −1.52 | 6.19 × 10−3 | MYO16 |
| chr14.0021177142 | −1.22 | 3.13 × 10−4 | −1.24 | 7.38 × 10−5 | |
| chr14.0021316565 | −1.29 | 2.23 × 10−2 | −1.56 | 2.05 × 10−4 | |
| chr14.0025947530 | 0.91 | 1.48 × 10−2 | 1.05 | 7.13 × 10−3 | |
| chr14.0080449863 | −1.84 | 5.11 × 10−5 | −1.74 | 2.05 × 10−4 | |
| chr14.0085404000 | −1.38 | 4.50 × 10−3 | −1.38 | 3.07 × 10−3 | |
| chr14.0104190006 | −1.48 | 3.71 × 10−3 | −1.75 | 2.66 × 10−4 | ZFYVE21 |
| chr15.0046178808 | −0.97 | 1.71 × 10−2 | −0.70 | 4.78 × 10−2 | RP11—718O11.1 |
| chr15.0069824154 | 1.42 | 1.25 × 10−4 | 1.55 | 4.82 × 10−6 | RP11—279F6.1 |
| chr15.0092982723 | 1.45 | 3.91 × 10−5 | 1.73 | 9.39 × 10−9 | ST8SIA2 |
| chr16.0004815786 | −0.89 | 8.94 × 10−4 | −0.92 | 9.24 × 10−3 | ZNF500 |
| chr16.0077912976 | −1.23 | 8.49 × 10−3 | −1.28 | 2.22 × 10−3 | VAT1L |
| chr16.0079468883 | 1.11 | 4.82 × 10−3 | 1.28 | 3.78 × 10−5 | |
| chr17.0018941025 | −1.85 | 1.91 × 10−3 | −1.96 | 2.09 × 10−4 | GRAP |
| chr17.0019045779 | −1.55 | 7.74 × 10−3 | −1.56 | 8.05 × 10−4 | GRAPL, CTC—457L16.2 |
| chr17.0028803808 | −1.20 | 1.47 × 10−2 | −1.24 | 4.72 × 10−3 | |
| chr17.0070499160 | 1.04 | 1.42 × 10−4 | 1.06 | 1.48 × 10−3 | LINC00511 |
| chr17.0074566299 | 0.87 | 3.28 × 10−2 | 1.14 | 3.76 × 10−4 | ST6GALNAC2, RP11—666A8.9 |
| chr18.0043923940 | −1.66 | 5.63 × 10−6 | −1.73 | 7.53 × 10−7 | RNF165 |
| chr18.0045011716 | 1.10 | 2.73 × 10−2 | 1.41 | 4.57 × 10−5 | CTD—2130O13.1 |
| chr18.0047177650 | −1.15 | 3.29 × 10−4 | −0.64 | 8.52 × 10−3 | |
| chr18.0047230566 | −1.39 | 1.98 × 10−2 | −1.30 | 3.48 × 10−3 | |
| chr18.0072250823 | 1.12 | 7.11 × 10−3 | 1.05 | 2.58 × 10−2 | CNDP1 |
| chr19.0002867898 | 1.36 | 5.19 × 10−9 | 1.12 | 1.72 × 10−2 | ZNF556 |
| chr19.0041126191 | −0.80 | 1.99 × 10−2 | −0.92 | 4.84 × 10−3 | LTBP4 |
| chr20.0031210733 | 1.20 | 2.29 × 10−2 | 1.36 | 2.68 × 10−2 | |
| chr20.0052825772 | −1.35 | 1.91 × 10−3 | −1.31 | 3.11 × 10−3 | PFDN4 |
| chr20.0055369320 | −1.24 | 9.46 × 10−4 | −1.68 | 1.37 × 10−4 | |
| chr20.0060501154 | 2.02 | 6.08 × 10−4 | 1.87 | 9.34 × 10−4 | CDH4 |
| chr21.0030689317 | −0.78 | 4.49 × 10−3 | −0.86 | 1.16 × 10−3 | BACH1 |
| chr22.0050332646 | −1.23 | 5.83 × 10−3 | −1.35 | 1.32 × 10−3 |
* LogFC = log2 fold change; positive logFC = hypermethylated in CP; negative logFC = hypomethylated in CP.