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. 2022 Dec 13;23(24):15795. doi: 10.3390/ijms232415795

Figure 5.

Figure 5

Concentration-dependent inhibitory effects of elacridar on hOCT2- and mOct2-mediated metformin (A) and MPP (B) transport in transfected HEK293 cells. Each data point represents the mean inhibitory effect (%) calculated from net-uptake of two independent experiments carried out in triplicate ± average deviation. IC50 values were calculated by sigmoidal 4Hill analysis using Sigma Plot version 13.0 software.