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Concentration-dependent inhibitory effects of imazalil on hOCT2- and mOct2-mediated metformin (A) and MPP (B) and transport in transfected HEK293 cells. Each data point represents the mean inhibitory effect (%) calculated from net-uptake of two independent experiments carried out in triplicate ± average deviation (AD). IC50 values were calculated by sigmoidal 4Hill equation using Sigma Plot version 13.0 software.
