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. 2022 Dec 10;10(12):2446. doi: 10.3390/microorganisms10122446

Table 3.

Synergistic antibacterial effects of thyme and cloves essential oils in binary combination against Escherichia coli and Staphylococcus aureus food isolates.

Bacterial Isolate Binary
Combinations
Individual FIC FIC Index (FICI) Interaction
Interpretation
E. coli mC1 thy-EO + cl-EO 0.500–0.130 0.630 synergy
S. aureus mC2 thy-EO + cl-EO 0.500–0.330 0.830 synergy

Thy-EO, thyme essential oil; cl-EO, cloves essential oil; FIC, fractional inhibitory concentration, FICI, fractional inhibitory concentration index; FICI ≤ 1.00, synergy; 1.00 < FICI ≤ 4.00, indifference; FICI > 4.00, antagonism.