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. 2022 Dec 1;12(12):1207. doi: 10.3390/metabo12121207

Figure 2.

Figure 2

Evaluation of depressive-like behaviour in mice following guanosine treatment and Aβ1–42 i.c.v. infusion. Mice subjected to Aβ1–42 infusion (400 pmol/site, i.c.v.) received guanosine (GUO, 8 mg/kg, i.p.) for seven days. On the eighth day, mice were subjected to the tail suspension test (A) and to the open field test (B). Values expressed as mean + S.E.M (n = 6) * p ≤ 0.05 compared with the vehicle-treated group; # p ≤ 0.05 compared with Aβ1–42 -treated group. (Two-way ANOVA followed by Tukey’s test).