Skip to main content
. 2022 Dec 8;27(24):8695. doi: 10.3390/molecules27248695

Figure 9.

Figure 9

Non-targeted metabolomics analysis presented key differential metabolites between LPS-challenged and pectolinarin mice. (A) Representative GC-MS total ion chromatograph of serum from the control group (Cont), LPS group, and pectolinarin (50 mg/kg)-treated group (PH) mice. (B) Multivariate statistical analysis of GC-MS metabolic profiling data. PCA scores plot and OPLS-DA scores plot were derived from GC-MS spectra of three groups of mice (LPS, blue dot; Cont, red dot; PH, green dot) and statistical validation of the OPLS-DA model by permutation testing. (C) Chemical classification of the key differential metabolites based on the annotations of Human Metabolome Database (www.hmdb.ca, accessed on 3 March 2022) and their corresponding percentages. (D) Cellular locations of the key differential metabolites based on the annotations of the Human Metabolome Database (www.hmdb.ca, accessed on 3 March 2022) and their corresponding percentages. PCA, principle component analysis; OPLS-DA, pair-wise orthogonal projections to latent structures discriminate analysis.