Table 1.
Target Glycogene | Upstream ncRNA | Downstream ncRNA | Downstream Target |
Tissue and Reference |
---|---|---|---|---|
A/B glycosyltransferases | miR-331-3p miR-1908-5p | Biosynthesis of AB0 antigens [18] | ||
ALG3 | miR-98-5p | Lung cancer [19] | ||
B3GNT3 | miR-149-5p | Lung cancer [20] | ||
B3GNT5 | miR1365-5p | MIR44352HG | Liver cancer [21] | |
B4GALT3 | miR-27 | β1 integrins | Cervical cancer [22] | |
miR-338-3p | DANCR | Neuroblastoma [23] | ||
B4GALT5 | miR-491-5p | circ_0009910 | miR-491-5p | Acute myeloid leukemia [24] |
C1GALT1 | miR-181d-5p | RAC1 | Lung cancer [25] | |
miR-1-3p | circ HP1BP3 | Bladder cancer [26] | ||
miR-124-3p | Aging colon [27] | |||
COSMC | miR-374b | IgA nephropathy [28] | ||
DPAGT1 | miR-485-5p | LINC00467 | Esophageal cancer [29] | |
FUT4 | miR-200c | Colorectal cancer [30] | ||
miR-26a/b | MALAT1 | PI3/AKT | Colorectal cancer [31,32] | |
miR-224-3p | Breast cancer [33] | |||
miR-493 | GAS6-AS2 | Breast cancer [34,35] | ||
miR-200c | Breast cancer [36] | |||
miR-493-5p | Breast cancer [34] | |||
miR-200b | Breast cancer [37] | |||
miR-371b-5p | AC114812.8 | Bladder cancer [38] | ||
miR-29b | Sp1 | CD44 | Leukemia stem cells [39] | |
HOXB-AS1 | Multiple myeloma [40] | |||
miR-199b-5p | Medulloblastoma [41] | |||
miR26a/b | NFkB | Osteoarthritis [42] | ||
miR200b | Arthritis [43] | |||
miR200c | Uterine receptivity [44] | |||
FUT5 | miR-125a-3p | PI3K/AKT | Colorectal cancer [45] | |
FUT6 | miR-125a-3p | PI3K/AKT | Colorectal cancer [45] | |
miR-326 | HOTAIR | CD44/PI3K/AKT | Colorectal cancer [46] | |
miR-106b | Breast cancer [47] | |||
FUT8 | miR-34a, miR-122 | Liver cancer [48] | ||
HOTAIR | JAK/STAT3 | Liver cancer [49] | ||
miR-198-5p | Lung cancer [50] | |||
miR-186 | SNHG1 | MMP2/MMP9 | Oral cancer [51] | |
miR-34c-5p | Renal interstitial fibrosis [52] | |||
GALNT1 | miR-129 | Bladder cancer [53] | ||
let-7i-5p | Kidney fibrosis [54] | |||
GALNT10 | mir-505 | DLGAP1-AS2 | Cholangiocarcinoma [55] | |
miR-122 | Liver cancer [56] | |||
GALNT14 | miR-125a | MMP2 and MMP9 | Ovarian cancer [57] | |
GALNT3 | miR-378a-3p | PSMA3-AS1 | PI3K/Akt | Ovarian cancer [58] |
GALNT4 | miR-506-3p | Lung cancer [59] | ||
miR-365b | Lung cancer [60] | |||
miR-9 | Liver cancer [61] | |||
GALNT7 | miR-30b/30d | Melanoma [62] | ||
miR-34a | SNHG7 | PI3K/Akt/mTOR | Colorectal cancer [63] | |
miR-30e | Cervical cancer [64] | |||
miR-214 | Cervical cancer [65] | |||
miR-34a/c | Laryngeal cancer [66] | |||
miR-214 | Esophageal cancer [67] | |||
miR-17-5p/miR-17-3p | Liver cancer [68] | |||
miR-30c | PI3K/AKT | Natural killer activity [69] in lung cancer | ||
miR-378 | Osteoblast differentiation [70] | |||
GCNT2 | miR-199a/b-5p | Colorectal cancer [71] | ||
GCNT3 | miR-15b | Pancreatic and colorectal cancer [72] | ||
miR-BART1-5p | EBV-induced gastric cancer [73] | |||
miR-195-5p | LINC00511 | Lung cancer [74] | ||
LGALS3 | miR-424-3p | Ovarian cancer [75] | ||
miR-128 | Colorectal cancer [76] | |||
miR-128-3p | Pancreatic cancer [77] | |||
miR-299-5p | circRERE | Apoptosis of nucleus polposum cells [78] | ||
LGALS9 | miR-455-5p | Colorectal cancer [79] | ||
miR-22 | Liver cancer [80] | |||
MGAT1 | LINC00173 | mucin 3A | Wilms’ tumor [81] | |
MGAT3 | miR-23b | Tau protein | Alzheimer’s disease [82] | |
MGAT4A | miR-424 | cyclin D1 | Breast cancer [83] | |
MGAT5 | miR-124 | Breast cancer [84] | ||
OGT | miR-485-5p | Esophageal cancer [85] | ||
miR-15a/miR-26a | Kidney cancer [86] | |||
miR-424-5p | XIST | Raf1 | Liver cancer [87] | |
miR-122 | RYR1 | Breast cancer [88] | ||
miR-15b | RORγt | Th17 differentiation [89] | ||
miR-423-5p | Apoptosis of cardiomyocytes [90] | |||
SIGLEC15 | miR-7109-3p | LINC00973 | Kidney cancer [91] | |
miR-582-5p | TUG1 | Liver cancer [92] | ||
ST3GAL1 | MEG3 | EGFR/PI3K/AKT | Kidney cancer [93] | |
ST3GAL2 | Gut infection [94] | |||
ST3GAL4 | miR-193a-3p miR-224 | PI3K/AKT | Kidney cancer [95] | |
miR-224, let-7i | Chronic myeloid leukemia [96] | |||
miR-370 | Colorectal cancer [97] | |||
miR193-b | CD44/NF-kB | Arthritis [98] | ||
ST3GAL5 | miR-26a, miR-548l, miR-34a | Liver cancer [99] | ||
ST3GAL6 | miR-26a | AKT/mTOR | Liver cancer [100] | |
ST3GAL6-AS1 | EGFR | Lung cancer [101] | ||
ST3GAL6-AS1 | MLL1 | ST3GAL6 | Colorectal cancer [102] | |
ST3GAL6-AS1 | HNRNPA2B1 | ST3GAL6 | Multiple myeloma [103] | |
ST6GAL1 | miR-9 | β1-integrins/FAK | Liver cancer [104] | |
miR-195-3p | TINCR | NFkB | Liver cancer [105] | |
miR-214-3p | Breast cancer [106] | |||
miR-150 | ZF-AS1 | EGFR/PI3K/Akt | Acute lymphoblastic leukemia [107] | |
miR-199a | ErbB2/ErbB3 | Various cancers [108] | ||
ST6GALNAC2 | miR-182/miR-135b | PI3K/AKT | Colorectal cancer [109,110] | |
ST6GALNAC4 | miR-4299 | Thyroid cancer [111] | ||
ST6GALNAC5 | miR-182 | Prostate cancer [112] | ||
ST8SIA1 | miR-33a/let-7e | Colorectal cancer [113] | ||
MIR44352HG | FAK/AKT/β-catenin | Prostate cancer [114] | ||
ST8SIA2 | miR-3072-3p | TUG1 | Brain ischemia [115] | |
ST8SIA4 | miR-26a/b | MALAT1 | Breast cancer [116,117] | |
miR-146a/b | PI3K-AKT-mTOR | Thyroid cancer [118] | ||
miR-144-5p/miR-451a | Cholangiocarcinoma [119] |