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(a) Schematic illustration of the O2-Cu/ZIF–8@Ce6/ZIF–8@F127 (OCZCF) nanoplatform as a drug carrier for enhanced cancer therapy. (b) Oxygen adsorption property of ZIF–8 and Cu-doped ZIF–8. (c) Oxygen release isotherm of ZIF–8. (d) Relative cell viability incubated with different MOF materials under normoxic or hypoxic conditions. (e) Relative tumor volume of tumor–bearing mice. Reproduced with permission from Ref. [124]. Copyright 2019, American Chemical Society.
