Table 6.

Biochemical parameters of the different experimental groups at the end of 14 days of topical vaginal treatment with crude extract (5, 10 and 15%) from E. uniflora.

Parameter	Naive	Placebo	5%	10%	15%
Total protein (g/dL)	6.14 ± 0.51	6.33 ± 1.11	6.33 ± 0.99	6.51 ± 0.97	6.61 ± 0.66
Albumin (g/dL)	4.11 ± 0.32	3.99 ± 0.66	3.92 ± 0.55	3.87 ± 0.77	4.02 ± 0.44
Globulin (g/dL)	2.33 ± 0.23	2.23 ± 0.33	2.45 ± 0.40	2.37 ± 0.33	2.24 ± 0.41
AST (U/L)	126.73 ± 41.23	121.66 ± 55.42	126.16 ± 56.56	120.42 ± 56.65	141.23 ± 42.31
ALT (U/L)	55.57 ± 11.20	61.12 ± 8.30	53.5 ± 9.98	52.65 ± 10.56	55.77 ± 11.20
GGT (U/L)	1.52 ± 0.54	1.47 ± 0.58	1.55 ± 0.59	1.57 ± 0.61	1.61 ± 0.54
AP (U/L)	104.15 ± 55.22	112.34 ± 47.49	114.10 ± 44.17	110.42 ± 51.15	109.15 ± 49.29
TB (mg/dL)	0.047 ± 0.017	0.046 ± 0.017	0.048 ± 0.019	0.049 ± 0.020	0.047 ± 0.017
TG (mg/dL)	77.12 ± 7.01	71.22 ± 8.12	70.77 ± 8.21	68.99 ± 9.99	68.19 ± 8.89
TC (mg/dL)	60.17 ± 11.02	61.57 ± 10.04	67 ± 8.02	66.15 ± 8.19	69.17 ± 10.22
HDL-C (mg/dL)	28.22 ± 6.14	30.29 ± 7.11	35.66 ± 9.99	32.77 ± 7.54	27.55 ± 5.55
VLDL-C (mg/dL)	13.12 ± 3.12	12.11 ± 3.01	12.14 ± 2.99	13.09 ± 3.99	14.82 ± 4.22
LDL-C (mg/dL)	21.11 ± 3.23	25.33 ± 4.11	24.13 ± 5.02	23.11 ± 4.99	20.92 ± 4.12
Creatinine (mg/dL)	0.33 ± 0.08	0.35 ± 0.09	0.39 ± 0.07	0.37 ± 0.08	0.36 ± 0.09
Urea (mg/dL)	50.01 ± 8.31	48.12 ± 6.99	49.22 ± 8.43	50.07 ± 9.31	52.66 ± 9.66
Progesterone (pg/mL)	28.06 ± 7.34	30.11 ± 6.16	30.22 ± 8.11	33.07 ± 9.31	28.21 ± 8.31
Estradiol (pg/mL)	47.22 ± 11.23	54.55 ± 12.21	52.01 ± 10.99	48.98 ± 8.99	45.22 ± 11.21
Free T3 (ng/mL)	0.52 ± 0.11	0.55 ± 0.10	0.52 ± 0.10	0.52 ± 0.10	0.53 ± 0.11
TSH (ng/mL)	4.71 ± 0.70	5.02 ± 0.72	4.93 ± 0.77	5.01 ± 0.89	4.98 ± 0.88

Statistical analyses were performed using one–way ANOVA followed by Bonferroni’s post-hoc test. Values are expressed as mean ± SEM (standard error of the mean). n = seven rats per group.