Figure 4.

Micellar curcumin potentiates the inhibition effect of erufosine on NF-κB and TWIST1 in the CTCL cell lines HuT-78 and MJ. Legend: MCRM—micellar curcumin; ERF—erufosine; (+) Co—nuclear extract of TNFα-activated HeLa cells; Co—untreated control; Combo—combination between erufosine and micellar curcumin with the same concentrations as by the single treatment; (A)—expression of TWIST1 by western blot after exposure of the cell lines to erufosine; (B)—expression ot TWIST1, p-Akt^Ser472 and p-Akt^Thr308 by western blot after exposure of the cell lines to the combinations; (C)—NF-κB p65 activity assay of ERF, MCRM and the combinations combination.