. 2022 Dec 4;12(12):1218. doi: 10.3390/metabo12121218

Table 2.

Association between the intra-assessment resting metabolic rate (RMR) variability expressed as a coefficient of variation (CV) for each of the assessed indirect calorimetry parameters, i.e., the CVs for volume of oxygen consumption (VO₂), volume of carbon dioxide production (VCO₂), respiratory exchange ratio (RER), and resting energy expenditure (REE), and different health-related parameters.

	CV for VO₂				CV for VCO₂				CV for RER				CV for REE
	Men		Women		Men		Women		Men		Women		Men		Women
	β	p	β	p	β	p	β	p	β	p	β	p	β	p	β	p
Anthropometry and body composition parameters
Weight (kg)	−0.100	0.558	0.103	0.851	−0.172	0.308	0.030	0.800	−0.158	0.351	−0.066	0.598	−0.154	0.362	−0.025	0.838
Height (cm)	0.070	0.695	0.067	0.580	0.067	0.709	−0.043	0.716	0.079	0.656	−0.123	0.317	0.134	0.453	−0.045	0.709
BMI (kg/m²)	−0.143	0.393	0.054	0.661	−0.215	0.193	0.040	0.740	−0.195	0.240	−0.009	0.942	−0.214	0.197	−0.013	0.916
Fat mass (kg)	−0.190	0.272	0.117	0.336	−0.244	0.155	0.064	0.594	−0.109	0.530	−0.065	0.603	−0.218	0.205	−0.022	0.855
Fat mass (%)	−0.210	0.231	0.081	0.508	−0.235	0.177	0.083	0.493	−0.061	0.729	−0.037	0.769	−0.228	0.192	−0.021	0.865
Fat free mass (kg)	0.093	0.585	0.040	0.745	0.010	0.953	−0.033	0.784	−0.177	0.291	−0.040	0.751	0.012	0.943	−0.033	0.783
Waist circumference (cm)	−0.086	0.613	0.126	0.301	−0.167	0.320	0.032	0.794	−0.257	0.122	−0.161	0.195	−0.256	0.125	−0.091	0.453
Cardiorespiratory fitness parameters
CRF (mL/min)	0.042	0.821	−0.017	0.894	−0.054	0.769	−0.048	0.698	−0.283	0.116	−0.006	0.964	−0.104	0.576	−0.060	0.623
CRF_BW (mL/[kg/BW]/min)	0.082	0.650	−0.135	0.273	0.068	0.706	−0.085	0.489	−0.112	0.530	0.084	0.507	0.063	0.728	−0.038	0.758
CRF_FFM (mL/[kg/FFM]/min)	0.005	0.978	−0.075	0.543	−0.038	0.835	−0.028	0.818	−0.177	0.325	0.049	0.696	−0.019	0.918	−0.048	0.693
Circulating cardiometabolic risk factors and blood pressure parameters
Glucose (mg/dL)	−0.158	0.390	0.071	0.560	−0.037	0.839	−0.014	0.907	0.260	0.153	−0.072	0.564	−0.025	0.893	−0.044	0.713
Insulin (UI/mL)	−0.185	0.299	0.199	0.096	−0.253	0.150	0.098	0.408	−0.017	0.925	−0.020	0.872	−0.277	0.123	0.081	0.499
HOMA index	−0.162	0.367	0.218	0.072	−0.140	0.436	0.159	0.186	0.022	0.904	−0.020	0.876	−0.157	0.391	0.127	0.289
Total cholesterol (mg/dL)	0.099	0.589	0.016	0.896	0.149	0.412	0.115	0.330	−0.056	0.761	0.004	0.974	0.030	0.873	0.074	0.528
HDL-C (mg/dl)	0.206	0.253	−0.148	0.224	0.182	0.313	−0.158	0.187	−0.119	0.514	−0.082	0.509	0.108	0.559	−0.162	0.177
LDL-C (mg/dl)	0.086	0.638	−0.014	0.906	0.132	0.468	0.092	0.435	−0.065	0.723	0.009	0.939	0.021	0.912	0.065	0.584
Triglycerides (mg/dl)	−0.002	0.990	−0.057	0.640	−0.051	0.781	−0.067	0.575	0.091	0.623	−0.043	0.728	−0.083	0.659	−0.140	0.240
Systolic BP (mm Hg)	0.081	0.656	0.046	0.701	−0.013	0.944	0.069	0.562	−0.231	0.196	0.049	0.692	−0.046	0.800	0.073	0.542
Diastolic BP (mm Hg)	−0.023	0.898	0.043	0.726	−0.148	0.395	−0.090	0.454	−0.235	0.170	−0.133	0.286	−0.264	0.123	−0.114	0.345
Cardiometabolic risk Z-score 1	−0.097	0.600	0.066	0.588	−0.152	0.409	0.046	0.701	−0.090	0.628	0.010	0.934	−0.229	0.218	−0.046	0.702
Cardiometabolic risk Z-score 2	−0.062	0.740	0.062	0.614	−0.129	0.487	0.070	0.562	−0.096	0.606	0.009	0.940	−0.195	0.296	−0.015	0.900
Heart rate and heart rate variability parameters
Mean HR (bpm)	−0.145	0.443	−0.039	0.771	−0.069	0.717	0.054	0.680	0.407	0.025	0.088	0.521	0.086	0.651	0.066	0.616
RMSSD (ms)	0.085	0.643	0.030	0.823	−0.015	0.933	−0.012	0.928	−0.364	0.039	−0.071	0.602	−0.040	0.828	−0.021	0.873
SDNN (ms)	0.070	0.702	−0.046	0.730	−0.023	0.900	−0.028	0.834	−0.330	0.062	0.071	0.606	−0.074	0.686	−0.028	0.833
pNN50 (%)	0.121	0.503	0.120	0.362	0.010	0.955	0.023	0.862	−0.376	0.031	−0.082	0.550	−0.047	0.795	0.036	0.787
HF (ms²)	0.074	0.683	0.018	0.891	−0.013	0.943	−0.076	0.563	−0.288	0.101	−0.074	0.586	−0.033	0.855	−0.025	0.848
HRV Z-score	0.047	0.800	−0.008	0.949	0.002	0.989	−0.044	0.737	−0.231	0.201	−0.070	0.611	−0.003	0.988	−0.026	0.844

Results are presented as standardized β and p-values from multiple linear regression analyses (adjusted for age). BMI: body mass index; CRF: cardiorespiratory fitness (i.e., peak VO₂ uptake); CRF_BW: CRF relative to body weight (peak VO₂ uptake/kg of body weight); CRF_FFM: CRF relative to fat free mass (peak VO₂ uptake/kg of fat-free mass); HOMA: homeostatic model assessment of insulin resistance index; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; BP, blood pressure; Cardiometabolic risk Z-scores 1 and 2: the first Z-score included classical metabolic syndrome markers (glucose, triglycerides, HDL-C, BP, and waist circumference), while the second included these classical metabolic syndrome markers and insulin-related markers (insulin and HOMA index) and total cholesterol and LDL-C Z-score values; HR: heart rate (in beats per minute [bpm]); RMSSD: the square root of the mean of the sum of the squares of the R-R interval differences; SDNN: standard deviation of normal R-R intervals; pNN50: the percentage of R-R intervals that shows a difference higher than 50 milliseconds (ms); HF: the power of the high frequency band (HF: 0.15–0.4 Hertz); HRV Z-score: heart rate variability Z-score including the RMSSD, the SDNN, the pNN50, and the HF time and frequency domains parameters’ Z-score values.