Table A2.
Full table of all the coefficients or error for the stereological markers counted in this study.
| Data File | Marker | Total Markers Counted | Number of Sampling Sites | Estimated Population Using Mean Section Thickness with Counts |
CE (Gundersen), m = 0 |
CE (Gundersen), m = 1 |
1st Estimated CE (Schmitz- Hof) |
2nd Estimated CE (Schmitz- Hof) |
|---|---|---|---|---|---|---|---|---|
| Amyloid-β | ||||||||
| LIC CN | Non-ir | 162 | 239 | 960,000.06 | 0.11 | 0.08 | 0.099 | 0.079 |
| LIC CN | Nuclear | 484 | 239 | 2,868,148.5 | 0.06 | 0.05 | 0.057 | 0.045 |
| LIC CN | Cytoplasmic | 7 | 239 | 41481.48 | 0.38 | 0.38 | 0.470 | 0.378 |
| LIC CN | Nuclear + cytoplasmic |
33 | 239 | 195,555.56 | 0.20 | 0.18 | 0.202 | 0.174 |
| LIC CN | All markers | 686 | 239 | 4,065,185.25 | 0.05 | 0.04 | 0.046 | 0.038 |
| LIC EC | Non-ir | 14 | 153 | 82,962.96 | 0.28 | 0.27 | 0.370 | 0.267 |
| LIC EC | Nuclear | 82 | 153 | 485,925.94 | 0.16 | 0.11 | 0.172 | 0.110 |
| LIC EC | Cytoplasmic | 1 | 153 | 5925.93 | 1.00 | 1.00 | 1.000 | 1.000 |
| LIC EC | Nuclear + cytoplasmic |
95 | 153 | 562,963 | 0.12 | 0.10 | 0.157 | 0.103 |
| LIC EC | All markers | 192 | 153 | 1,137,777.88 | 0.1 | 0.07 | 0.109 | 0.072 |
| LVCN | Non-ir | 45 | 137 | 44,444.45 | 0.21 | 0.15 | 0.312 | 0.149 |
| LVCN | Nuclear | 128 | 137 | 126,419.76 | 0.13 | 0.09 | 0.105 | 0.088 |
| LVCN | Cytoplasmic | 11 | 137 | 10,864.20 | 0.34 | 0.30 | 0.343 | 0.302 |
| LVCN | Nuclear + cytoplasmic |
65 | 137 | 64,197.54 | 0.14 | 0.12 | 0.129 | 0.124 |
| LVCN | All markers | 249 | 137 | 245,925.94 | 0.1 | 0.07 | 0.083 | 0.063 |
| Fibronectin | ||||||||
| LIC CN | Non-ir | 594 | 235 | 3,520,000.25 | 0.05 | 0.04 | 0.049 | 0.041 |
| LIC CN | Cytoplasmic | 217 | 235 | 1,285,926.13 | 0.09 | 0.07 | 0.085 | 0.068 |
| LIC CN | Nuclear + cytoplasmic |
129 | 235 | 764,444.5 | 0.12 | 0.09 | 0.100 | 0.088 |
| LIC CN | All markers | 940 | 235 | 5,570,370.5 | 0.04 | 0.03 | 0.045 | 0.033 |
| LIC EC | Non-ir | 147 | 100 | 871,111.19 | 0.10 | 0.08 | 0.123 | 0.082 |
| LIC EC | Cytoplasmic | 35 | 100 | 207,407.41 | 0.19 | 0.17 | 0.192 | 0.169 |
| LIC EC | Nuclear + cytoplasmic |
28 | 100 | 165,925.92 | 0.22 | 0.19 | 0.222 | 0.189 |
| LIC EC | All markers | 210 | 100 | 1,244,444.5 | 0.09 | 0.07 | 0.103 | 0.069 |
| LVCN | Non-ir | 300 | 145 | 296,296.31 | 0.12 | 0.06 | 0.099 | 0.058 |
| LVCN | Cytoplasmic | 77 | 145 | 76,049.38 | 0.12 | 0.11 | 0.133 | 0.114 |
| LVCN | Nuclear + cytoplasmic |
62 | 145 | 61,234.57 | 0.14 | 0.13 | 0.137 | 0.127 |
| LVCN | All markers | 439 | 145 | 433,580.28 | 0.1 | 0.05 | 0.072 | 0.048 |
| TDP-43 | ||||||||
| LIC CN | Non-ir | 555 | 248 | 3,288,889 | 0.07 | 0.04 | 0.051 | 0.042 |
| LIC CN | Nuclear | 74 | 248 | 438,518.59 | 0.12 | 0.12 | 0.118 | 0.116 |
| LIC CN | Cytoplasmic | 60 | 248 | 355,555.56 | 0.16 | 0.13 | 0.170 | 0.129 |
| LIC CN | Nuclear + cytoplasmic |
140 | 248 | 829,629.63 | 0.12 | 0.09 | 0.108 | 0.085 |
| LIC CN | All markers | 829 | 248 | 49,12593 | 0.05 | 0.04 | 0.044 | 0.035 |
| LIC EC | Non-ir | 130 | 106 | 770,370.5 | 0.14 | 0.09 | 0.150 | 0.088 |
| LIC EC | Nuclear | 35 | 106 | 207,407.41 | 0.19 | 0.17 | 0.218 | 0.169 |
| LIC EC | Cytoplasmic | 17 | 106 | 100,740.75 | 0.24 | 0.24 | 0.253 | 0.243 |
| LIC EC | Nuclear + cytoplasmic |
63 | 106 | 373,333.34 | 0.16 | 0.13 | 0.161 | 0.126 |
| LIC EC | All markers | 245 | 106 | 1,451,852 | 0.12 | 0.07 | 0.11 | 0.064 |
| LVCN | Non-ir | 151 | 140 | 149,135.81 | 0.14 | 0.09 | 0.112 | 0.081 |
| LVCN | Nuclear | 47 | 140 | 46,419.76 | 0.19 | 0.15 | 0.150 | 0.146 |
| LVCN | Cytoplasmic | 22 | 140 | 21,728.40 | 0.22 | 0.21 | 0.217 | 0.213 |
| LVCN | Nuclear + cytoplasmic |
53 | 140 | 52,345.68 | 0.29 | 0.15 | 0.148 | 0.137 |
| pNFP | ||||||||
| LIC CN | Axonal | 3970 | 213 | 2,299,468,544 | 0.06 | 0.02 | - | - |
| LIC EC | Axonal | 1795 | 76 | 1,058,085,632 | 0.09 | 0.03 | - | - |
| LVCN | Axonal | 1988 | 115 | 195,308,656 | 0.13 | 0.04 | - | - |
| Iba-1 | ||||||||
| LIC CN | Microglial | 2738 | 227 | 405,629,632 | 0.06 | 0.02 | 0.035 | 0.019 |
| LIC EC | Microglial | 2135 | 122 | 316,296,320 | 0.08 | 0.03 | 0.047 | 0.022 |
| LVCN | Microglial | 1594 | 139 | 39,358,024 | 0.09 | 0.03 | 0.055 | 0.025 |
| GFAP | ||||||||
| LIC CN | Astrocytic | 4840 | 229 | 717,036,992 | 0.05 | 0.02 | 0.03 | 0.014 |
| LIC EC | Astrocytic | 2662 | 96 | 394,370,400 | 0.08 | 0.03 | 0.058 | 0.019 |
| LVCN | Astrocytic | 3128 | 137 | 77,234,568 | 0.08 | 0.02 | 0.043 | 0.018 |