Table 1.
Treatment | PGE2 Release (pg/mL) ± SD |
VEGF Release (pg/mL) ± SD |
---|---|---|
None | 78 ± 8.2 | 41.6 ± 3.8 |
Dexamethasone 10 nM | 40.6 ± 5.3 * | 32.3 ± 3.1 * |
Cisplatin 30 μM | 232.4 ± 21.6 * | 131.6 ± 11.4 * |
Cisplatin 30 μM + Dexamethasone 10 nM | 108.5 9.1 § | 78.1 ±6.9 § |
Cell culture supernatants from BCPs in the absence (none treatment) and the presence of 30 mM cisplatin, with or without 10 nM dexamethasone, were assayed for PGE2 production and VEGFA release. Values are from three independent experiments (n = 3). The non-parametric Mann-Whitney test was used for pairwise comparisons. * p < 0.05 vs. cells without treatment; § p < 0.05 vs. cells treated with cisplatin.