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. 2022 Nov 23;10(12):2321. doi: 10.3390/microorganisms10122321

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of GRC fermented with different lactic acid bacteria stains on nitric oxide (NO) production (A) RAW264.7 cells were treated with GRC-SC11, GRC-SC64, GRC-Bro17, GRC-ON188, GRC-S. pum8, GRC. Nitrite levels in the culture media were determined using Griess reagent and were presumed to reflect NO levels. (B) RAW264.7 cells were treated with various concentrations (0.25%, 0.50%, and 1.00%) of GRC-SC11, GRC-ON188, GRC-Bro17, GRC-S. pum8, GRC-SC64, GRC for 24 h. RAW264.7 cell viability was assessed using CCK-8 assay. One-way analysis of variance was used for the comparison of group means, followed by Dunnett’s t-test (* p < 0.05, ** p < 0.01, *** p < 0.001 vs. control (con)).