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iCAF-related subtypes had distinct dysregulated pathways: (A) Cluster 2 was related to a worse prognosis in TCGA-BLCA. (B) Consensus TCGA molecular subtypes between two clusters. (C) The enrichment activity of 26 stemness-related signatures between two clusters. (D) Upregulated cancer hallmarks of Cluster 1 (left) and Cluster 2 (right). (E) Upregulated pathways of Cluster 2. (F) Immunotherapy response prediction.
