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. 2022 Nov 26;14(12):2605. doi: 10.3390/pharmaceutics14122605

Table 1.

Dysopsonins.

Name of the
Protein
How Dysopsonins Affect Uptake of NPs in
Macrophages
Type of NP Studied
HRG Stealth properties SiO2-NPs [51,52]
Apos Modulation of C activation PEG-NPs (Apo-J) [14]
PS-NPs [14]
SiO2-NPs (Apo-J) [74]
AgNPs (Apo-J) [74]
Decrease in clearance speed Liposomes (Apo-AI) [75]
HSA Stealth properties PS microparticles [76]
HA-NPs [77]
Decrease in clearance speed PHBHHx NPs (BSA) [74]
SP-A and SP-D Hypothesis: inhibition of NPs’ agglomeration PS-NPs (SP-A) [23]
CNTs (SP-D) [23]

HRG: histidine-rich glycoprotein; SiO2-NPs: silica nanoparticles; AgNPs: silver NPs; Apos: apolipoproteins; HSA: human serum albumin; PS: polystyrene; HA: hyaluronic acid; BSA: bovine serum albumin; PHBHHx: poly-3-hydroxybutyrate-co-3-hydroxyhexanoate; SP-A and SP-D: surfactant protein A and D; CNTs: carbon nanotubes.