FIG. 1.

U. urealyticum antigen-induced NO production by alveolar macrophages. Macrophages were stimulated with U. urealyticum (4 × 10⁶ to 4 × 10⁸ CCU/ml) or LPS (100 ng/ml), or in combination with IFN-γ (100 IU/ml). NO production was assessed by determining the NO₂⁻ concentration in conditioned medium. (A) A dose-related induction of NO was seen after 24 h of stimulation with U. urealyticum. (B) Kinetics of NO production by macrophages in response to 4 × 10⁸ CCU of U. urealyticum/ml.