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Abilities of BCG vaccines to sensitize guinea pigs to cutaneous DTH. Data are mean induration size 24 and 48 h after intradermal injection of bovine PPD. Animals were inoculated with 5 × 104 CFU of BCG Pasteur, BCG methionine auxotroph (Met−), BCG leucine auxotroph (Leu−), or PBS and 5 weeks later were tested by intradermal injection of 50 IU of bovine standard PPD.
